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Additional info for Alzheimer's disease and related disorders annual. / 2004
21,29–33 A possiblemechanism for the reported association between hypertension and AD may be that ischemic WMLs increase the possibility that individuals with Alzheimer lesions in their brains express a dementia syndrome. 35 Clinical diagnosis The typical clinical picture of AD is a dementia with insidious onset and a slowly progressive loss of memory and other cognitive functions, affecting language, visuospatial abilities, executive function, orientation, praxis, and behavior. NINCDS-ADRDA criteria36 state that the diagnosis of probable AD requires the absence of systemic disorders or other brain diseases that, alone, could account for the dementia.
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